Global renal perfusion pressure, which is the difference between MAP and central venous pressure (CVP), becomes the difference between MAP and intra-abdominal pressure (IAP) when IAP is elevated, such as in intra-abdominal hypertension or abdominal compartment syndrome Renal perfusion is necessary to maintain normal urine output. Inadequate renal perfusion decreases GFR and increases tubular resorptive mechanisms as described earlier. Reduced cardiac output or hypotension causes decreased renal perfusion.
In the physiology of the kidney, renal blood flow (RBF) is the volume of blood delivered to the kidneys per unit time. In humans, the kidneys together receive roughly 25% of cardiac output, amounting to 1.2 - 1.3 L/min in a 70-kg adult male. It passes about 94% to the cortex. RBF is closely related to renal plasma flow (RPF), which is the volume of blood plasma delivered to the kidneys per unit time.
Global renal perfusion pressure, which is the difference between MAP and central venous pressure (CVP), becomes the difference between MAP and intra-abdominal pressure (IAP) when IAP is elevated, such as in intra-abdominal hypertension or abdominal compartment syndrome